First Zika vaccine to be tested in humans #progress

Reported by CNN:

(CNN)The first human trial of a Zika vaccine will begin soon, Inovio Pharmaceuticals said Monday.

Inovio, which is based in Plymouth Meeting, Pennsylvania, and GeneOne Life Science, which is based in Seoul, South Korea, worked together on the vaccine. They previously collaborated to create vaccines for Ebolaand MERS, both of which are being tested.

The Zika vaccine, with the clinical-sounding name GLS-5700, will first be tested in 40 healthy volunteers. The first tests in humans should start in the next few weeks, Inovio said in a news release.
In the animal testing stage, the vaccine caused a strong antibody response, the company said. It is still very early in the vaccine’s development. Phase I of a vaccine trial ensures that it can be tolerated well in human subjects. If successful in this first round of human testing, it will need additional approval for further testing.
At the next stage, the vaccine would be tested on people who have Zika. Then there would be a stage to see how well it works on a larger group of people. Dr. Anthony Fauci, director of the National Institute for Allergy and Infectious Disease at the National Institutes of Health, is leading a team that is trying a few approaches to a vaccine, including an approach using DNA like Inovio’s does. He believes that trial could start by the end of August. In the coming months, he said, we will probably be hearing about a number of vaccine candidates going into Phase I trials. “This is all good news,” Fauci said.
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