Treating asthma by targeting the immune system? – T cells take my breath away! #science #twinning

A new connection between asthma and T cells in the immune system!! Props to my twin brother – one of the authors, and the featured scientist in the NIH video below! More info from the NIAID here – paper in Science Translational Medicine here, and featured summary –  T cell types that take your breath away.

A new study has shown that targeting two immune cells—Th2 and Th17—and their downstream, inflammatory effects is better than targeting just one pathway in the context of asthma. The researchers also show that blocking the Th2 pathway, which is a target of commonly-prescribed corticosteroid drugs, may unexpectedly boost conditions for Th17-driven inflammation. These results clarify how immune cells and their products contribute to asthma, and the work may enable researchers to design and test therapies that target both pathways. The study appears in the August 19, 2015, edition of Science Translational Medicine and included scientists from NIAID, the University of Leicester, and Genentech.

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Amazing video of immune cells attacking worm #science @JExpMed

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JEM

A very cool report published in the Journal of Experimental Medicine out of UCSF provides dazzling images and videos of immune cells in action! More info and abstract here at Pubmed, and links to actual video on Facebook here. Gif credit: CauseScience.

The immune system in action! This 11-second video shows how white blood cells (eosinophils) attack a parasitic worm in 80 mins.
Watch more fascinating videos from Steven Rosen and colleagues [UC San Francisco (UCSF)] in their recent JEM study on the immune response to parasites.

Also, shout out to the nematode C elegans! But for future reference, C elegans are not a parasitic worm in humans. Very cool to see an academic journal spreading cool science images on social media! Way to go JEM!!

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