CauseScience Friday – Nov 6th #Science #WeveBeenBusy #Selfie

Both of us at CauseScience have been extremely busy lately… so busy that we haven’t had time for our CauseScience Friday posts! So today, we’ll give a little taste of what we’ve been up to lately:


Crestwind24– I have previously posted about imaging of a really cool neuron in male C. elegans, as well as ablating it (killing it) and seeing what happened to the behavior of the worms. Now that I have a better idea of what that neuron does, I can test its function on behavior more finely. Today I am doing an experiment using a drug that causes accumulation of the neurotransmitter acetylcholine in the synapse, aldicarb. Using this drug, I can test the neurons function in a behavior that requires acetylcholine signaling! I am testing aldicarb on normal worms, as well as on worms that I ablated the neuron. To do this, I put the drug on the plates that the worms crawl around on, then time how long it takes for the worms to perform the behavior I am testing!!


pgurel– As you may recall, I’ve been doing Cryo-EM to look at the structure of actin filaments. After collecting several images of my sample, to obtain a structure, a LOT of processing and refinement of the images must be done. This takes several days to do, but in the end, you (hopefully) get a nice 3D reconstruction of your sample, in my case, actin. Basically, I’ve been sitting in front of my computer for several days, and apart from my screen looking like a war zone, you can see my 3D reconstruction on the right side in purple!



Help us do science! I’ve teamed up with researcher Paige Brown Jarreau to create a survey of CauseScience readers. By participating, you’ll be helping me improve CauseScience and contributing to SCIENCE on blog readership. You will also get FREE science art from Paige’s Photography for participating, as well as a chance to win a t-shirt or a $50.00 Amazon gift card (100 available).
It should only take 5-10 minutes to complete. You can find the survey here:

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