The CDC and WHO have updated the case counts for this week, with the total deaths in West Africa at 5,147.
The Liberian President has ended the state of emergency that was declared to control the ebola outbreak in that country.
Doctors Without Borders said it will host clinical trials starting next month in three Ebola treatment centers experimenting with drugs for off-label uses, shortening the usual lengthy process used to find treatments through study with animals and healthy people.
The trials’ protocols are in the final stages of development and are designed with a simple target of 14-day survival and with broad inclusion criteria. The protocols will ensure that disruption to patient care will be minimal, that internationally-accepted medical and research ethical standards are respected, and that sound scientific data will be produced and shared for public good. The main principles and designs have been shared with the respective countries’ ethical authorities, with the goal of starting the first trials during December 2014. Initial results could be available in February 2015.
The two drugs, brincidofovir and favipiravir, were selected from WHO’s shortlist of potential Ebola treatments after careful review of safety and efficacy profiles, product availability, and ease of administration to patients.
Join Doctors Without Borders/Médecins Sans Frontières (MSF) on November 13 at 8:00 PM EST for a special update on the Ebola crisis in West Africa.
The panel will include MSF aid workers recently returned from assignments in Guinea and Liberia, along with members of MSF headquarters staff. This wide-ranging discussion will include first-hand accounts of working with patients and communities, the ongoing problem of fear and stigma in West Africa and here in the US, and the challenges facing the international community going forward.