Problems with reproducibility in science? Here are the NIH proposed principles and guidelines to fix it! #science


In June, the National Institutes of Health, Nature, and Science convened a meeting with editors from over 40 top academic science journals to address problems of reproducibility in preclinical research reported in these journals. The result of this meeting is the “Proposed Principles and Guidelines for Reporting Preclinical Research,” now available on the NIH website.

The principles and guidelines include:

1. Rigorous Statistical Analysis

2. Transparency in Reporting (based on this paper)

3. Data and Material Sharing

4. Consideration of Refutations

5. Consider establishing best practice guidelines for image based data and description of biological reagents

Below is the intro for the proposal, defining who it applies to etc.

The signatories represent journals that publish preclinical biological research — an area of research that encompasses both exploratory studies and hypothesis-testing studies, with many different designs. The reproducibility of these studies is expected to vary. The journals agree to adhere to the following principles with the aim of facilitating the interpretation and repetition of experiments as they have been conducted in the published study. These measures and principles do not obviate the need for replication and reproduction in subsequent investigations to establish the robustness of published results across multiple biological systems.

It is great to see action happening on this front, especially action that appears to be so united~!


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